Retinol derivative ,Anti-aging active Hydroxypinacolone Retinoate 10%,
Anti-aging, anti-wrinkle, HPR, Hydroxypinacolone Retinoate 10%,
Cosmate®HPR10,also named as Hydroxypinacolone Retinoate 10%,HPR10, with INCI name Hydroxypinacolone Retinoate and Dimethyl Isosorbide,is formulated by Hydroxypinacolone Retinoate with Dimethyl Isosorbide,it is a an ester of all-trans Retinoic Acid,which are natural and synthetic derivatives of vitamin A,capable of binding to retinoid receptors.The binding of retinoid receptors can enhance gene expression, which effectively turns key cellular functions on and off.
Cosmate®HPR,Hydroxypinacolone Retinoate is a retinol derivative, which has the function of regulating the metabolism of the epidermis and stratum corneum, can resist aging,can reduce sebum spillage, dilute epidermal pigments, play a role in preventing skin aging,preventing acne, whitening and light spots.While ensuring the powerful effect of retinol, it also greatly reduces its irritation.It is currently used for anti-aging and prevention of acne recurrence.
Key Functions of Hydroxypinacolone Retinoate (HPR10) 10%
*Anti-Aging & Collagen Boosting:Reduces the appearance of wrinkles, fine lines, and sagging skin by stimulating collagen and elastin synthesis.
*Skin Texture Refinement:Accelerates cellular turnover to smooth rough texture, minimize pores, and promote a radiant complexion. *Hyperpigmentation Correction:Inhibits melanin overproduction to fade dark spots, sun damage, and uneven skin tone. *Acne Management:Regulates sebum production and prevents pore congestion, reducing breakouts and blemishes.
How Hydroxypinacolone Retinoate (HPR10) 10% Works
Hydroxypinacolone Retinoate 10% (HPR10) combines advanced science for unparalleled efficacy:Its bioactive retinoid ester structure allows direct activation of retinoic acid receptors (RARs) in the skin, bypassing the multi-step conversion required by traditional retinol to deliver faster,irritation-free results.Enhanced by a lipid-based encapsulated delivery system,HPR penetrates deeply into skin layers for sustained release,ensuring prolonged collagen stimulation and cellular renewal. Additionally,HPR’s photostable formula resists sunlight degradation.
Advantages and Benefits of Hydroxypinacolone Retinoate (HPR10) 10%
*Gentle Formula for All Skin Types:Zero to minimal irritation, ideal for sensitive skin or first-time retinoid users.
*Faster Visible Results:Direct receptor targeting ensures quicker improvements in texture,tone,and firmness.Safe for nighttime and daytime use ,thanks to photostability and non-irritating properties. *Multi-Action Solution:Addresses aging,acne,pigmentation, and texture concerns in one formula. *Superior Stability:Resists oxidation and degradation, maintaining potency over time.
Key Technical Parameters:
Appearance | Transparent Yellow Liquid |
Assay | 9.5~10.5% |
Refractive Index | 1.450~1.520 |
Specific Gravity | 1.10~1.20g/ml |
Heavy Metals | 10 ppm max. |
Arsenic | 3 ppm max. |
Tretinoin | 20 ppm max. |
Isotretinoin | 20 ppm max. |
Total Plate Counts | 1,000 cfu/g max. |
Yeasts & Molds | 100 cfu/g max. |
E.Coli | Negative |
Application:*Anti-Aging Agent,*Anti-Wrinkle,*Skin Conditioning,*Whitening Agent,*Anti-Acne,*Anti-SpotHPR10: A Revolutionary Retinoid-Based Formulation
Introduction
HPR10 is a cutting-edge skincare ingredient formulated with a powerful blend of Hydroxypinacolone Retinoate (HPR) and Dimethyl Isosorbide. As an ester of all-trans Retinoic Acid, HPR belongs to the family of retinoids—natural and synthetic derivatives of vitamin A—renowned for their ability to interact with retinoid receptors in the skin. This unique composition combines the efficacy of retinoids with enhanced stability and skin compatibility, making it a standout choice for modern skincare formulations.
Key Functions
HPR10 delivers multiple benefits tailored to skin health and rejuvenation:
Promotes Cellular Turnover: It stimulates the renewal of skin cells, helping to shed dull, dead skin layers and reveal a smoother, more radiant complexion.
Reduces Signs of Aging: By activating retinoid receptors, it targets fine lines, wrinkles, and loss of elasticity, supporting a firmer, more youthful appearance over time.
Improves Skin Texture: Regular use helps minimize the appearance of pores, uneven skin tone, and roughness, resulting in a refined and balanced skin surface.
Enhances Skin Barrier Function: Unlike some traditional retinoids, HPR10 supports the skin’s natural protective barrier, reducing the risk of irritation while maintaining hydration.
Working Principle
At the core of HPR10’s effectiveness is its interaction with retinoid receptors (RARs and RXRs) in the skin. As an ester of all-trans Retinoic Acid, HPR is designed to be gently metabolized by the skin, where it binds to these receptors to trigger a cascade of biological responses. This includes upregulating genes involved in cell regeneration, collagen production, and antioxidant activity. The inclusion of Dimethyl Isosorbide enhances the penetration and bioavailability of HPR, ensuring it reaches deeper skin layers to exert its benefits without causing excessive irritation— a common concern with stronger retinoids.
Advantages
Gentle Yet Effective: Compared to harsh retinoids like retinoic acid, HPR10 minimizes irritation, making it suitable for sensitive skin types while retaining powerful anti-aging properties.
Stable Formulation: Its chemical structure resists degradation from light and oxidation, ensuring longer shelf life and consistent performance in skincare products.
Versatile Compatibility: It integrates well with other skincare ingredients (e.g., hyaluronic acid, vitamin C) without compromising efficacy, allowing for flexible formulation in serums, creams, and lotions.
Targeted Action: By specifically binding to retinoid receptors, it delivers focused results, addressing aging signs and texture issues without unnecessary disruption to healthy skin functions.
Applications
HPR10 is ideal for a wide range of skincare products and user needs:
Anti-Aging Formulations: Serums, night creams, and treatments aimed at reducing wrinkles, fine lines, and sagging skin.
Texture-Improving Products: Masks, toners, and moisturizers designed to smooth rough skin and refine pores.
Sensitive Skin Solutions: Gentle formulations for users who want retinoid benefits without redness or peeling.
Daily Skincare Routines: Can be incorporated into both morning and evening regimens (when paired with sunscreen during the day) for long-term skin health maintenance.
In summary, HPR10 represents a breakthrough in retinoid technology, offering a balance of potency, stability, and gentleness that makes it a valuable addition to modern skincare.
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