Polydeoxyribonucleotide(PDRN), promotes skin regeneration, enhances moisturizing effect, and fades signs of aging

Polydeoxyribonucleotide(PDRN)

Short Description:

PDRN (Polydeoxyribonucleotide) is a specific DNA fragment extracted from salmon germ cells or salmon testes, with a 98% similarity in base sequence to human DNA. PDRN (Polydeoxyribonucleotide), a bioactive compound derived from sustainably sourced salmon DNA, powerfully stimulates skin’s natural repair mechanisms. It boosts collagen, elastin, and hydration for visibly reduced wrinkles, accelerated healing, and a stronger, healthier skin barrier. Experience rejuvenated, resilient skin.


  • Trade Name: Cosmate®PDRN
  • Product Name: Polydeoxyribonucleotide
  • INCI Name: Sodium DNA
  • CAS No.: 100403 - 24 - 5
  • Product Detail

    Why Zhonghe Fountain

    Product Tags

    Polydeoxyribonucleotide(PDRN), a purified polynucleotide extract sourced from the testes of deep-sea salmon, has emerged as a star ingredient in high-end cosmetic formulations. This natural biomolecule, with a structure akin to the nucleic acids in human skin cells, offers a gentle yet powerful approach to skincare. Through a meticulous extraction and purification process, PDRN retains its bioactivity, ensuring it seamlessly interacts with the skin’s cellular machinery. Unlike harsh synthetic compounds, its marine-derived origin guarantees exceptional biocompatibility, making it suitable for all skin types—including sensitive and mature skin. In cosmetic products, PDRN works beneath the surface to address the root causes of skin aging and dullness, promoting natural repair and renewal. It has become a sought-after ingredient in serums, masks, and creams, beloved for its ability to transform skin texture, restore elasticity, and reveal a healthy, luminous glow.​

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    Key Function​ of Polydeoxyribonucleotide(PDRN)

    Stimulates collagen and elastin synthesis to improve skin firmness and reduce wrinkles.​

    Enhances skin hydration by boosting the skin’s natural moisture-retention capacity.​

    Accelerates the renewal of epidermal cells, promoting a smoother, more even skin tone.​

    Reduces redness and calms irritated skin by modulating inflammatory responses.​

    Supports the skin’s barrier function, protecting against environmental stressors.

    Mechanism of Action of Polydeoxyribonucleotide(PDRN)

    PDRN exerts its effects by penetrating the upper layers of the skin and binding to specific receptors on keratinocytes and fibroblasts—key cells responsible for skin structure and repair. This interaction triggers a signaling cascade that activates fibroblast activity, leading to increased production of collagen, elastin, and hyaluronic acid, which are essential for maintaining skin elasticity and hydration. PDRN also inhibits pro-inflammatory mediators, reducing skin sensitivity and redness. Additionally, it promotes angiogenesis in the dermal layer, enhancing blood flow to deliver nutrients and oxygen to skin cells, further supporting their health and vitality. By mimicking the skin’s natural repair processes, PDRN helps reverse the signs of aging and environmental damage, resulting in a rejuvenated appearance.​

    Benefits and Advantages​ of Polydeoxyribonucleotide(PDRN)

    Natural & Gentle: Marine-derived and biocompatible, suitable for sensitive skin with minimal risk of irritation.​

    Anti-Aging Powerhouse: Diminishes fine lines, wrinkles, and sagging by boosting collagen and elastin production.​

    Improves Skin Texture: Smoothens rough patches and uneven tone for a silky, touchable complexion.​

    Long-Lasting Hydration: Enhances the skin’s ability to retain moisture, keeping it plump and dewy all day.​

    Supports Skin Barrier: Strengthens the skin’s protective layer, defending against pollution, UV damage, and free radicals.​

    Visible Results: Delivers noticeable improvements in skin radiance and youthfulness with consistent use.​

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    Key Technical Specifications

     ITEMS

    STANDARD

    Appearance White, white-like or light yellow powder
    Identification UV: Ratio of absorbance at 260 and 280nm

    1.5~2.0

    pH Value (1% aqueous solution) 5.0~9.0
    Assay 90.0% min
    Loss on Drying 20.0% max.
    Average molecular weight 1000 KDa max.
    Lead 10mg/kg max.
    Cadmium 5mg/kg max.
    Arsenic 2mg/kg max.
    Mercury 1mg/kg max.
    Aerobic bacterial count 1000 cfu/g max.
    Molds & Yeast count 100cfu/g max.
    Thermotolerant coliform bacteria Negative/g
    Pseudomonas aeruginosa Negative/g

    Application​s:

    Anti-Aging Serums: Concentrated PDRN serums target deep wrinkles, firming the skin and restoring elasticity.​

    Hydrating Masks: Overnight or sheet masks infused with PDRN provide intense moisture and promote overnight repair.​

    Revitalizing Creams: Daily moisturizers with PDRN offer ongoing support for skin renewal and barrier health.​

    Brightening Treatments: Formulations combining PDRN with vitamin C or niacinamide to even skin tone and reduce dark spots.​

    Post-Sun Care Products: Soothes sun-damaged skin, reduces redness, and aids in restoring its natural balance.​

    Eye Contour Products: Targets fine lines, puffiness, and dark circles around the delicate eye area for a refreshed look.

     


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