The New Anti-Aging Retinoid—Hydroxypinacolone Retinoate (HPR)

Hydroxypinacolone Retinoate (HPR) is an ester form of retinoic acid. It is unlike retinol esters, which require a minimum of three conversion steps to reach the active form; due to its close relation to retinoic acid (it is a retinoic acid ester), Hydroxypinacolone Retinoate (HPR) does not need to go through the same steps of conversion as other retinoids do – it is already bioavailable to the skin as it is. 

Hydroxypinacolone Retinoate 10%(HPR10) is formulated by Hydroxypinacolone Retinoate with Dimethyl Isosorbide.It is a an ester of all-trans Retinoic Acid,which are natural and synthetic derivatives of vitamin A, capable of binding to retinoid receptors. The binding of retinoid receptors can enhance gene expression, which effectively turns key cellular functions on and off.


Benefits of Hydroxypinacolone Retinoate(HPR):

•Increased Collagen Production

Collagen is one of the most common proteins in the human body. It‘s found in our connective tissue (tendons, etc) as well as hair and nails.Depleted collagen and skin elasticity also contribute to large pores as the skin sags and stretches the pore, making it appear bigger. This can happen regardless of skin type, although if you have a lot of natural oils it may be more noticeable.Hydroxypinacolone Retinoate (HPR) helped increase collagen levels in participants’ skin.

•Increased Elastin In The Skin

Hydroxypinacolone Retinoate (HPR) increases Elastin in the skin. Elastin fibers give our skin the ability to stretch and snap back into place. As we lose elastin our skin starts to sag and droop. Along with collagen, elastin keeps our skin smooth and supple, which makes for a firm, younger looking appearance.

•Reduce Fine Lines and Wrinkles

Reducing the appearance of wrinkles is probably the most common reason that women start using retinoids. It normally starts with fine lines around our eyes, and then we begin to notice bigger wrinkles on our forehead, between the eyebrows, and around the mouth. Hydroxypinacolone Retinoate (HPR)  are the top treatment for wrinkles. They are effective at both reducing the appearance of wrinkles and at preventing new ones.

•Fade Age Spots

Also known as hyperpigmentation, dark spots on our skin can occur at any age but tend to be more common as we get older. They are mostly caused by sun exposure and they are worse during the summer. Hydroxypinacolone Retinoate (HPR) would work well on hyperpigmentation since most retinoids do. There’s no reason to expect Hydroxypinacolone Retinoate (HPR) to be any different. 

•Improve Skin Tone

Hydroxypinacolone Retinoate (HPR) actually make our skin feel and look younger.Hydroxypinacolone Retinoate (HPR) increase the speed of skin cell turnover, creating improved skin tone. 

HPR benifit

 How does Hydroxypinacolone Retinoate (HPR) work within the skin?

Hydroxypinacolone Retinoate (HPR) can directly bind to retinoid receptors within the skin although it’s a modified ester form of retinoic acid.  This sets off a chain reaction that results in new cells being created including essential ones that go into creating collagen and elastin fibers. It also helps stimulate cell turnover.  The underlying network of collagen and elastin fibers and other essential cells within the dermis becomes thicker, replete with healthy, living cells just like younger skin.  It does this with significantly less irritation than the equivalent concentration of retinol and better potency than other Vitamin A analogs like retinol esters like retinyl palmitate.  


Post time: Jul-28-2023