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Theobromine

Short Description:

In cosmetics, theobromine plays an important role in skin – conditioning. It can promote blood circulation, help reduce puffiness and dark circles under the eyes. In addition, it has antioxidant properties, which can scavenge free radicals, protect the skin from premature aging, and make the skin more youthful and elastic. Due to these excellent properties, theobromine is widely used in lotions, essences, facial toners and other cosmetic products.

Trade Name: Cosmate ®TB

Product Name: Theobromine

INCI Name: Theobromine

Molecular Formula: C7H8N4O2

CAS No.: 83-67-0

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Product Detail

Why Zhonghe Fountain

Product Tags

Theobromine, a key cosmetic ingredient, offers multiple skincare benefits. It enhances blood circulation, effectively reducing under-eye puffiness and dark circles by promoting fluid drainage. Its mild lipolytic properties help break down subcutaneous fat, aiding in cellulite reduction, making it ideal for body contouring products.

As an antioxidant, it neutralizes free radicals, protecting skin from environmental damage and premature aging, thus maintaining elasticity and a youthful appearance. It also soothes mild skin irritation, supporting a balanced complexion.

Compatible with other ingredients like hyaluronic acid and vitamins, theobromine amplifies overall skincare efficacy. Widely used in serums, eye creams, and body lotions, it’s valued for its versatility and gentle action across various skin types.

Key Functions of Theobromine

Circulation Boost: Enhances cutaneous microcirculation, aiding fluid drainage to reduce under-eye puffiness and diminish dark circles by improving blood flow in delicate areas like the periorbital region.
Antioxidant Defense: Neutralizes free radicals caused by UV radiation and pollution, protecting skin cells from oxidative damage, which helps delay premature aging (e.g., fine lines, loss of elasticity).
Mild Lipolysis Support: Assists in breaking down subcutaneous fat deposits, making it useful in cellulite-targeted body care products to refine skin texture.
Soothing & Calming: Alleviates mild skin irritation and redness by modulating inflammatory responses, suitable for sensitive or reactive skin formulations.
Synergistic Compatibility: Works well with ingredients like hyaluronic acid (hydration) and vitamin C (brightening), amplifying overall skincare efficacy without harsh side effects.

Mechanism of Action of Theobromine

Vasomodulation: As a mild phosphodiesterase inhibitor, it relaxes smooth muscle cells in microvessels, dilating capillaries to enhance cutaneous microcirculation. This improves nutrient delivery, accelerates fluid drainage, and reduces stagnation—key for alleviating under-eye puffiness and dark circles.
Antioxidant Activity: Scavenges reactive oxygen species (ROS) generated by UV exposure and pollution, interrupting oxidative chains that damage collagen and elastin. This preserves skin structural integrity, slowing premature aging.
Lipolytic Regulation: Modulates adipocyte metabolism by inhibiting cyclic AMP breakdown, promoting triglyceride hydrolysis in subcutaneous fat. This aids in reducing cellulite appearance in body care products.
Anti-inflammatory Effects: Downregulates pro-inflammatory cytokines (e.g., TNF-α, IL-6), calming mild irritation and redness, supporting barrier balance in sensitive skin formulations.
Synergistic Enhancement: Works with antioxidants (e.g., vitamin E) and humectants (e.g., glycerin) to amplify their effects, boosting overall product efficacy without compromising skin tolerance.

Benefits and Advantages of Theobromine

Multi-Functional Efficacy: Combines circulatory enhancement, antioxidant protection, mild lipolysis, and soothing properties, addressing diverse concerns (puffiness, aging, cellulite, irritation) in a single ingredient.
Gentle Action: Unlike harsher stimulants, it acts mildly on skin, making it suitable for sensitive or delicate areas (e.g., under eyes), minimizing irritation risks.
Natural Origin: Derived from cacao, it aligns with consumer demand for plant-based ingredients, enhancing product appeal in clean beauty trends.
Synergistic Potential: Works harmoniously with common skincare components (hyaluronic acid, vitamins, peptides), amplifying their effects without compatibility issues.
Broad Application: Integrates seamlessly into various products—eye creams, serums, body lotions, anti-aging formulas—due to its versatile functionality.

Key Technical Parameters

Technical Parameter	Cosmetic-Relevant Characteristics
Purity	Typically ≥98% (USP/FCC grade), ensuring minimal impurities that may cause skin irritation or formulation instability.
Physical Form	White to off-white crystalline powder with 80–200 mesh particle size, facilitating easy dispersion in aqueous/oil-based formulations.
Solubility	Slightly soluble in water (≈0.05 g/100 mL at 25°C); enhanced in hot water/alkaline solutions, requiring pH adjustment for uniform blending.
pH Stability Range	Stable at pH 4–8, compatible with most skincare formulations (serums, creams, lotions) without degradation.
Melting Point	Approximately 357°C, ensuring thermal stability during manufacturing processes (heating, sterilization).
Heavy Metal Limit	≤10 ppm, meeting cosmetic safety standards to prevent skin toxicity.
Microbial Count	≤100 CFU/g, avoiding contamination that could compromise product shelf life or cause skin infections.