Licochalcone A is a premium phytochemical extracted from the roots of Glycyrrhiza glabra (licorice), a plant with a rich history in traditional medicine for its healing properties. Through modern extraction techniques, this potent compound is harnessed to deliver targeted benefits to the skin. Unlike harsh synthetic ingredients, Licochalcone A works in harmony with the skin’s natural processes, making it ideal for even the most delicate or reactive skin types. Its versatility shines in a range of cosmetic formulations, where it not only addresses visible signs of irritation but also helps maintain the skin’s barrier function, promoting long-term resilience. Backed by cosmetic science, Licochalcone A has become a sought-after ingredient for brands prioritizing efficacy, safety, and natural origins.
Key Functions of Licochalcone A
Powerful Anti-Inflammatory Action: Mitigates skin inflammation and redness.
Soothing Sensation: Calms irritated or sensitized skin.
Antioxidant Protection: Fights free radicals to prevent premature aging.
Sebum Regulation: Helps balance oil production in acne-prone skin.
Barrier Support: Strengthens the skin’s natural protective layer.
Mechanism of Action of Licochalcone A
Licochalcone A exerts its effects by inhibiting key inflammatory mediators, such as prostaglandins and leukotrienes, which are responsible for triggering redness and irritation. It also modulates the activity of enzymes involved in oxidative stress, neutralizing free radicals that damage skin cells and accelerate aging. Additionally, it interacts with skin receptors to regulate sebum secretion, reducing the likelihood of clogged pores and breakouts. By supporting the synthesis of ceramides—lipids critical for barrier integrity—it enhances the skin’s ability to retain moisture and fend off external aggressors.
Benefits and Advantages of Licochalcone A
Gentle for Sensitive Skin: Non-irritating formula suitable for rosacea, post-procedure, or easily reactive skin.
Multi-Tasking Efficacy: Combines anti-inflammatory, antioxidant, and balancing benefits in one ingredient.
Natural Origin: Derived from sustainable licorice sources, aligning with clean beauty trends.
Stable in Formulations: Compatible with various skincare bases (creams, serums, toners) and resistant to pH fluctuations.
Non-Comedogenic: Does not clog pores, making it safe for acne-prone skin.
Key Technical Specifications
| Items | Specification |
| Description | Yellow to yellowish – brown powder |
| Odor & Taste | Characteristic |
| Loss on Drying | NMT 5.0% |
| Residue on Ignition | NMT 2.0% |
| Iodine Colour Number (0.035% in Butyleneglycol) | NMT 9 |
| Aflatoxin B1 | NMT 2 ppb |
| Summ of Aflatoxin B1, B2, G1, G2 | NMT 4 ppb |
| Ochratoxin A | NMT 60 ppb |
| Sieve Test(Passes through) – 80 mesh | Not less than 90% pass |
| Heavy metals | NMT 2.0 ppm (µg/g) |
| Lead (Pb) | NMT 0.5 ppm (µg/g) |
| Arsenic (As) | NMT 0.5 ppm (µg/g) |
| Antimony (Sb) | NMT 0.5 ppm (µg/g) |
| Cadmium (Cd) | NMT 0.1 ppm (µg/g) |
| Mercury (Hg) | NMT 0.1 ppm (µg/g) |
| Chromium (Cr) | NMT 5.0 ppm (µg/g) |
| Nickel (Ni) | NMT 10 ppm (µg/g) |
| Microbiology – Total Plate Count | NMT 1000 cfu/gram |
| Mould & Yeast | NMT 100 cfu/gram |
| E. Coil | Negative |
| Salmonella | Negative |
| Pesticides | Negative |
| Licochalcone A | HPLC: NLT 21.0% |
Application
Licochalcone A is a versatile ingredient integrated into numerous cosmetic products, including:
Sensitive Skin Serums: To calm redness and discomfort.
Acne Treatment Gels: To reduce inflammation and prevent breakouts.
Post-Sun Care Products: To soothe sun-exposed, irritated skin.
Anti-Aging Moisturizers: To protect against oxidative damage and support barrier health.
Rosacea-Specific Formulations: To alleviate persistent redness and sensitivity.
Baby Skincare: Gentle enough for delicate infant skin prone to irritation.
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