Glabridin, is hailed as “Whitening Gold”,the Premium Multi-Functional Skincare Ingredient

Glabridin

Short Description:

Glabridin, a rare flavonoid extracted from the roots of Glycyrrhiza glabra (licorice), is hailed as “Whitening Gold” in cosmetics. Renowned for its potent yet gentle effects, it delivers brightening, anti-inflammatory, and antioxidant benefits, making it a star ingredient in high-end skincare formulations.


  • Trade Name: Cosmate​® GLA
  • Product Name: Glabridin
  • INCI Name: Glabridin
  • Molecular Formula: C20H20O4
  • CAS No.: 59870-68-7
  • Function: Whitening
  • Product Detail

    Why Zhonghe Fountain

    Product Tags

    Glabridin stands out as one of the most bioactive compounds in licorice extract, prized for its scarcity and versatility. Only a very small amount of glabridin can be extracted from 1 ton of licorice roots. its extraction is highly intricate, contributing to its premium status. Unlike many traditional brightening ingredients, glabridin offers a unique combination of efficacy and mildness: it powerfully inhibits melanin production while soothing irritated skin and combating free radicals, making it suitable even for sensitive and delicate skin types.​

    In cosmetic applications, glabridin excels at addressing multiple skin concerns simultaneously. It targets hyperpigmentation such as sun spots, melasma, and post-acne marks, evens out uneven skin tone, and enhances radiance. Beyond brightening, its anti-inflammatory properties calm redness and sensitivity, while its antioxidant capacity helps delay signs of aging, making it a multi-tasking ingredient that fulfills “brightening + repairing + anti-aging” needs.​

    组合1

    Key Functions​ of Glabridin

    Potent Brightening & Spot Reduction: Inhibits tyrosinase activity (a key enzyme in melanin synthesis), reducing melanin production, fading existing spots, and preventing new pigmentation.​

    Anti-Inflammatory & Soothing: Reduces the release of pro-inflammatory cytokines (e.g., IL-6, TNF-α), alleviating skin redness and sensitivity, and repairing the skin barrier.​

    Antioxidant & Anti-Aging: Scavenges free radicals, minimizes oxidative damage to the skin, and delays aging signs like fine lines and sagging.​

    Skin Tone Regulation: Improves uneven skin tone, boosts skin translucency, and promotes a naturally fair and healthy complexion.​

    Mechanism of Action​ of Glabridin

    Melanin Synthesis Inhibition: Competitively binds to the active site of tyrosinase, directly blocking the formation of melanin precursors (dopaquinone) and preventing pigment accumulation at the source.​

    Anti-Inflammatory Repair Pathway: Inhibits the NF-κB inflammatory signaling pathway, reducing inflammation-induced pigmentation (e.g., acne marks) and promoting stratum corneum repair to enhance skin resistance.​

    Antioxidant Protection: Its molecular structure captures and neutralizes free radicals, protecting collagen and elastic fibers from oxidative damage, thus maintaining skin elasticity and firmness.​

    Benefits and Advantages​ of Glabridin

    Gentle & Safe: Non-cytotoxic with extremely low skin irritation, suitable for all skin types, including sensitive skin and pregnant skin.​

    Multi-Functional: Combines brightening, anti-inflammatory, and antioxidant effects, enabling comprehensive skincare without the need for multiple ingredients.​

    High Stability: Resistant to light and heat, maintaining its activity in cosmetic formulations to ensure long-lasting efficacy.​

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    KEY TECHNICAL PARAMETERS

    Appearance White powder
    Purity (HPLC) Glabridin≥98%
    Test of flavone Positive
    Physical characteristics
    Particle-size NLT100% 80 Mesh
    Loss on drying ≤2.0%
    Heavy metal
    Total metals ≤10.0ppm
    Arsenic ≤2.0ppm
    Lead ≤2.0ppm
    Mercury ≤1.0ppm
    Cadmium ≤0.5 ppm
    Microorganism
    Total number of bacteria ≤100cfu/g
    Yeast ≤100cfu/g
    Escherichia coli Not included
    Salmonella Not included
    Staphylococcus Not included

    Applications:

    Glabridin is widely used in various high-end skincare products, such as:​

    Brightening Serums: As a core ingredient, specifically fading spots and enhancing radiance.​

    Repairing Creams: Combined with moisturizing ingredients to soothe sensitivity and strengthen the skin barrier.​

    Post-Sun Repair Products: Alleviating UV-induced inflammation and pigmentation.​

    Luxury Masks: Providing intensive brightening and anti-aging care to improve overall skin quality.

     


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