China High Grade Fermented Active Cosmetic Ingredient Ergothioneine CAS 497-30-3

Ergothioneine

Short Description:

Cosmate^®EGT,Ergothioneine (EGT),as a kind of rare amino acid, can be initially found in mushrooms and cyanobacteria,Ergothioneine is a unique sulfur containing amino acid that cannot be synthesized by human and is only available from certain dietary sources,Ergothioneine is a naturally occurring amino acid that is synthesized exclusively by fungi, mycobacteria and cyanobacteria.

Trade Name: Cosmate®EGT

Product Name: Ergothioneine

INCI Name: Ergothioneine

Molecular Formula: C9H15N3O2S

CAS No.: 497-30-3

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Cosmate^®EGT,Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions.

Cosmate^®EGT is a potent antioxidant and has proven to protect the skin against sun damage and other signs of aging. Cosmate^®EGT protects cells from damage caused by ultraviolet rays. It reduces reactive oxygen species in the body and may help repair DNA damaged by ultraviolet rays. It also inhibits the apoptotic response of cells exposed to UVA rays, increasing their viability.Ergothioneine has a powerful cytoprotective effect. Cosmate^®EGT anti-inflammatory and antioxidant properties used in sunscreen cosmetics. UVA in the sun can penetrate into the skin dermis and affect the growth of epidermal cells, making the skin surface cells aging earlier, and UVB is easy to lead to skin cancer. Ergothione was found to minimize the formation of reactive oxygen species and protect cells from radiation damage. It also stimulates collagen production in the skin and decreases inflammation. As one of the last organs to receive nutrients, it is essential to provide it with these nutrients in skincare products. At physiological concentrations, ergothioneine exhibits a potent controlled diffusional inactivation of hydroxyl radicals and prevents the generation of atomic oxygen, which protects erythrocytes from neutrophils from normally functioning or moribulently inflammatory sites. When combined with other antioxidants and skin care products, ergothioneine is effective in reducing the signs of aging and improving the overall appearance of the skin.

Technical Parameters:

Appearance	White Powder
Assay	99% min.
Loss on Drying	1% max.
Heavy Metals	10 ppm max.
Arsenic	2 ppm max.
Lead	2 ppm max.
Mercury	1 ppm max.
E.Coli	Negative
Total Plate Count	1,000cfu/g
Yeast & Mold	100 cfu/g