alpha-Bisabolol,Anti-inflammatory and Skin barrier

Alpha-Bisabolol

Short Description:

A versatile, skin-friendly ingredient derived from chamomile or synthesized for consistency, bisabolol is a cornerstone of soothing, anti-irritant cosmetic formulations. Renowned for its ability to calm inflammation, support barrier health, and enhance product efficacy, it’s the ideal choice for sensitive, stressed, or acne-prone skin.​


  • Trade Name: Cosmate ®Bisab
  • Product Name: alpha-Bisabolol
  • INCI Name: Bisabolol
  • Molecular Formula: C15H26O
  • CAS No.: 515-69-5
  • Product Detail

    Why Zhonghe Fountain

    Product Tags

    Alpha Bisabolol, scientifically classified as a monocyclic sesquiterpene alcohol, stands out in the cosmetic industry for its exceptional balance of gentleness and performance. Naturally abundant in German chamomile (Matricaria chamomilla) essential oil—where it can constitute over 50% of the oil’s composition—it is also produced synthetically to ensure consistent quality and supply. This clear to pale yellow, slightly viscous liquid boasts excellent skin compatibility, high permeability, and stability across a range of pH levels and formulations, making it a favorite among formulators.​Whether sourced from nature or lab-synthesized, bisabolol delivers identical soothing benefits, making it a versatile addition to everything from daily moisturizers to targeted treatments. Its mild, subtle aroma and low irritation potential align with consumer demands for “clean” and “sensitive-skin-safe” ingredients, while its proven track record in reducing redness and supporting recovery solidifies its role as a trusted active in premium skincare lines.​

     

    组合1

     

    Key Function​ of Alpha Bisabolol

    Calms skin irritation and reduces visible redness​

    Mitigates inflammation caused by environmental stressors or product use​

    Strengthens the skin’s natural barrier function​

    Enhances the efficacy of other active ingredients through improved penetration​

    Exhibits mild antimicrobial properties to support skin microbiome balance​

    Mechanism of Action​ of Alpha Bisabolol

    Bisabolol exerts its effects through multiple biological pathways:​

    Anti-Inflammatory Activity: It inhibits the release of pro-inflammatory mediators such as leukotrienes and interleukin-1, interrupting the cascade that leads to redness, swelling, and discomfort.​

    Barrier Support: By stimulating keratinocyte proliferation and migration, it accelerates the repair of damaged skin barriers, reducing transepidermal water loss (TEWL) and enhancing moisture retention.​

    Penetration Enhancement: Its lipophilic structure allows it to permeate the stratum corneum efficiently, facilitating the delivery of co-formulated actives (e.g., vitamins, antioxidants) deeper into the skin.​

    Antimicrobial Effects: It disrupts the growth of harmful bacteria (e.g., Propionibacterium acnes) and fungi, helping to prevent breakouts and maintain a healthy skin microbiome.​

    Benefits and Advantages​ ​ of Alpha Bisabolol

    Suitable for All Skin Types: Particularly beneficial for sensitive, reactive, or post-procedure skin, with a proven safety profile even for infants and acne-prone complexions.​

    Formulation Flexibility: Compatible with creams, serums, sunscreens, and wipes; stable in both water-based and oil-based products.​

    Synergistic with Other Actives: Enhances the performance of ingredients like vitamin C, retinol, and niacinamide by reducing potential irritation and boosting absorption.​

    组合2

    Key Technical Parameters 

    Appearance Colorless to light yellow liquid
    Identification Positive
    Odor Characteristic
    Purity ≥98.0%
    Specific optical rotation -60.0°~-50.0°
    Density(20,g/cm3) 0.920-0.940
    Refractive index(20) 1.4810-1.4990
    Ash ≤5.0%
    Loss on drying ≤5.0%
    Residue Ignition ≤2.0%
    Heavy Metals ≤10.0ppm
    Pb ≤2.0ppm
    As ≤2.0ppm
    Total of bacteria ≤1000cfu/g
    Yeast and Mold ≤100cfu/g
    Salmgosella Negative
    Coli Negative

    Application​

    Bisabolol integrates seamlessly into a wide range of cosmetic products, including:​

    Sensitive Skin Care: Calming toners, moisturizers, and overnight masks to alleviate redness and discomfort.​

    Acne Treatments: Spot treatments and cleansers to reduce inflammation without drying the skin.​

    Sun Care & After-Sun Products: Added to sunscreens to mitigate UV-induced stress; key in after-sun lotions to soothe burns or peeling.​

    Baby & Pediatric Formulations: Gentle lotions and diaper creams to protect delicate skin from irritation.​

    Post-Treatment Recovery: Serums and balms for use after chemical peels, laser therapy, or shaving to support healing.​

    Anti-Aging Products: Combined with antioxidants to address inflammation-related signs of aging, such as dullness and uneven texture.​

     


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